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human kidney cancer caki 1 cells  (ATCC)


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    ATCC human kidney cancer caki 1 cells
    Human Kidney Cancer Caki 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1515 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/kidney+cancer+cell+caki+1/Caki-1/10__1016_slash_j__fbio__2023__103501-75-0-14
    Average 97 stars, based on 1515 article reviews
    human kidney cancer caki 1 cells - by Bioz Stars, 2026-09
    97/100 stars

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    Article Title: Genetically engineered vaccinia viruses
    Article Snippet: .. Examples of cancer cells to be used for the evaluation include the malignant melanoma cell RPMI-7951 (for example, ATCC HTB-66), the lung adenocarcinoma HCC4006 (for example, ATCC CRL-2871), the lung carcinoma A549 (for example, ATCC CCL-185), the small cell lung cancer cell DMS 53 (for example, ATCC CRL-2062), the lung squamous cell carcinoma NCI-H226 (for example, ATCC CRL-5826), the kidney cancer cell Caki-1 (for example, ATCC HTB-46), the bladder cancer cell 647-V (for example, DSMZ ACC 414), the head and neck cancer cell Detroit 562 (for example, ATCC CCL-138), the breast cancer cell JIMT-1 (for example, DSMZ ACC 589), the breast cancer cell MDA-MB-231 (for example, ATCC HTB-26), the esophageal cancer cell OE33 (for example, ECACC 96070808), the glioblastoma U-87MG (for example, ECACC 89081402), the neuroblastoma GOTO (for example, JCRB JCRB0612), the myeloma RPMI 8226 (for example, ATCC CCL-155), the ovarian cancer cell SK-OV-3 (for example, ATCC HTB-77), the ovarian cancer cell OVMANA (for example, JCRB JCRB1045), the colon cancer cell RKO (for example, ATCC CRL-2577), the colorectal carcinoma HCT 116 (for example, ATCC CCL-247), the pancreatic cancer cell BxPC-3 (for example, ATCC CRL-1687), the prostate cancer cell LNCaP clone FGC (for example, ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (for example, JCRB JCRB0435), the mesothelioma NCI-H28 (for example, ATCC CRL-5820), the cervical cancer cell SiHa (for example, ATCC HTB-35), and the gastric cancer cell Kato III (for example, RIKEN BRC RCB2088). ..

    Article Title: Genetically engineered vaccinia viruses
    Article Snippet: .. Examples of cancer cells to be used for the evaluation include the malignant melanoma cell RPMI-7951 (for example, ATCC HTB-66), the lung adenocarcinoma HCC4006 (for example, ATCC CRL-2871), the lung carcinoma A549 (for example, ATCC CCL-185), the small cell lung cancer cell DMS 53 (for example, ATCC CRL-2062), the lung squamous cell carcinoma NCI-H226 (for example, ATCC CRL-5826), the kidney cancer cell Caki-1 (for example, ATCC HTB-46), the bladder cancer cell 647-V (for example, DSMZ ACC 414), the head and neck cancer cell Detroit 562 (for example, ATCC CCL-138), the breast cancer cell JIMT-1 (for example, DSMZ ACC 589), the breast cancer cell MDA-MB-231 (for example, ATCC HTB-26), the esophageal cancer cell OE33 (for example, ECACC 96070808), the glioblastoma U-87MG (for example, ECACC 89081402), the neuroblastoma GOTO (for example, JCRB JCRB0612), the myeloma RPMI 8226 (for example, ATCC CCL-155), the ovarian cancer cell SK-OV-3 (for example, ATCC HTB-77), the ovarian cancer cell OVMANA (for example, JCRB JCRB1045), the colon cancer cell RKO (for example, ATCC CRL-2577), the colorectal carcinoma HCT 116 (for example, ATCC CCL-247), the pancreatic cancer cell BxPC-3 (for example, ATCC CRL-1687), the prostate cancer cell LNCaP clone FGC (for example, ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (for example, JCRB JCRB0435), the mesothelioma NCI-H28 (for example, ATCC CRL-5820), the cervical cancer cell SiHa (for example, ATCC HTB-35), and the gastric cancer cell Kato III (for example, RIKEN BRC RCB2088). ..

    Article Title: Recombinant vaccinia virus and methods of use thereof
    Article Snippet: .. Examples of cancer cells to be used for the evaluation include the malignant melanoma cell RPMI-7951 (for example, ATCC HTB-66), the lung adenocarcinoma HCC4006 (for example, ATCC CRL-2871), the lung carcinoma A549 (for example, ATCC CCL-185), the lung carcinoma HOP-62 (for example, DCTD Tumor Repository), the lung carcinoma EKVX (for example, DCTD Tumor Repository), the small cell lung cancer cell DMS 53 (for example, ATCC CRL-2062), the lung squamous cell carcinoma NCI-H226 (for example, ATCC CRL-5826), the kidney cancer cell Caki-1 (for example, ATCC HTB-46), the bladder cancer cell 647-V (for example, DSMZ ACC 414), the head and neck cancer cell Detroit 562 (for example, ATCC CCL-138), the breast cancer cell JIMT-1 (for example, DSMZ ACC 589), the breast cancer cell MDA-MB-231 (for example, ATCC HTB-26), the breast cancer cell MCF7 (for example, ATCC HTB-22), the breast cancer HS-578T (for example, ATCC HTB-126), the breast ductal carcinoma T-47D (for example, ATCC HTB-133), the esophageal cancer cell OE33 (for example, ECACC 96070808), the glioblastoma U-87MG (for example, ECACC 89081402), the neuroblastoma GOTO (for example, JCRB JCRB0612), the myeloma RPMI 8226 (for example, ATCC CCL-155), the ovarian cancer cell SK-OV-3 (for example, ATCC HTB-77), the ovarian cancer cell OVMANA (for example, JCRB JCRB1045), the cervical cancer cell line HeLa (for example, ATCC CCL-2), the colon cancer cell RKO (for example, ATCC CRL-2577), the colon cancer cell HT-29 (for example, ATCC HTB-38), the colon cancer Colo 205 (for example, ATCC CCL-222), the colon cancer SW620 (for example, ATCC CCL-227), the colorectal carcinoma HCT 116 (for example, ATCC CCL-247), the pancreatic cancer cell BxPC-3 (for example, ATCC CRL-1687), the bone osteosarcoma U-2 OS (for example, ATCC HTB-96), the prostate cancer cell LNCaP clone FGC (for example, ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (for example, JCRB JCRB0435), the mesothelioma NCI-H28 (for example, ATCC CRL-5820), the cervical cancer cell SiHa (for example, ATCC HTB-35), and the gastric cancer cell Kato III (for example, RIKEN BRC RCB2088). ..

    Article Title: Genetically engineered vaccinia viruses
    Article Snippet: .. The evaluated cells were the malignant melanoma cell RPMI-7951 (ATCC HTB-66), the lung adenocarcinoma HCC4006 (ATCC CRL-2871), the lung carcinoma A549 (ATCC CCL-185), the small cell lung cancer cell DMS 53, the lung squamous cell carcinoma NCI-H226 (ATCC CRL-5826), the kidney cancer cell Caki-1 (ATCC HTB-46), the bladder cancer cell 647-V (DSMZ ACC 414), the head and neck cancer cell Detroit 562 (ATCC CCL-138), the breast cancer cell JIMT-1 (DSMZ ACC 589), the breast cancer cell MDA-MB-231 (ATCC HTB-26), the esophageal cancer cell OE33 (ECACC 96070808), the glioblastoma U-87MG (ECACC 89081402), the neuroblastoma GOTO (JCRB JCRB0612), the myeloma RPMI 8226 (ATCC CCL-155), the ovarian cancer cell SK-OV-3 (ATCC HTB-77), the ovarian cancer cell OVMANA (JCRB JCRB1045), the colon cancer cell RKO (ATCC CRL-2577), the colorectal carcinoma HCT 116, the pancreatic cancer cell BxPC-3 (ATCC CRL-1687), the prostate cancer cell LNCaP clone FGC (ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (JCRB JCRB0435), the mesothelioma NCI-H28 (ATCC CRL-5820), the cervical cancer cell SiHa (ATCC HTB-35) and the gastric cancer cell Kato III (RIKEN BRC RCB2088). .. The media used were RPMI1640 medium (Sigma-Aldrich Co.

    Article Title: Genetically engineered vaccinia viruses
    Article Snippet: .. The evaluated cells were the malignant melanoma cell RPMI-7951 (ATCC HTB-66), the lung adenocarcinoma HCC4006 (ATCC CRL-2871), the lung carcinoma A549 (ATCC CCL-185), the small cell lung cancer cell DMS 53, the lung squamous cell carcinoma NCI-H226 (ATCC CRL-5826), the kidney cancer cell Caki-1 (ATCC HTB-46), the bladder cancer cell 647-V (DSMZ ACC 414), the head and neck cancer cell Detroit 562 (ATCC CCL-138), the breast cancer cell JIMT-1 (DSMZ ACC 589), the breast cancer cell MDA-MB-231 (ATCC HTB-26), the esophageal cancer cell OE33 (ECACC 96070808), the glioblastoma U-87MG (ECACC 89081402), the neuroblastoma GOTO (JCRB JCRB0612), the myeloma RPMI 8226 (ATCC CCL-155), the ovarian cancer cell SK-OV-3 (ATCC HTB-77), the ovarian cancer cell OVMANA (JCRB JCRB1045), the colon cancer cell RKO (ATCC CRL-2577), the colorectal carcinoma HCT 116, the pancreatic cancer cell BxPC-3 (ATCC CRL-1687), the prostate cancer cell LNCaP clone FGC (ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (JCRB JCRB0435), the mesothelioma NCI-H28 (ATCC CRL-5820), the cervical cancer cell SiHa (ATCC HTB-35) and the gastric cancer cell Kato III (RIKEN BRC RCB2088). .. The media used were RPMI1640 medium (Sigma-Aldrich Co.

    Article Title: Recombinant vaccinia virus and methods of use thereof
    Article Snippet: .. Examples of cancer cells to be used for the evaluation include the malignant melanoma cell RPMI-7951 (for example, ATCC HTB-66), the lung adenocarcinoma HCC4006 (for example, ATCC CRL-2871), the lung carcinoma A549 (for example, ATCC CCL-185), the lung carcinoma HOP-62 (for example, DCTD Tumor Repository), the lung carcinoma EKVX (for example, DCTD Tumor Repository), the small cell lung cancer cell DMS 53 (for example, ATCC CRL-2062), the lung squamous cell carcinoma NCI-H226 (for example, ATCC CRL-5826), the kidney cancer cell Caki-1 (for example, ATCC HTB-46), the bladder cancer cell 647-V (for example, DSMZ ACC 414), the head and neck cancer cell Detroit 562 (for example, ATCC CCL-138), the breast cancer cell JIMT-1 (for example, DSMZ ACC 589), the breast cancer cell MDA-MB-231 (for example, ATCC HTB-26), the breast cancer cell MCF7 (for example, ATCC HTB-22), the breast cancer HS-578T (for example, ATCC HTB-126), the breast ductal carcinoma T-47D (for example, ATCC HTB-133), the esophageal cancer cell 0E33 (for example, ECACC 96070808), the glioblastoma U-87MG (for example, ECACC 89081402), the neuroblastoma GOTO (for example, JCRB JCRB0612), the myeloma RPMI 8226 (for example, ATCC CCL-155), the ovarian cancer cell SK-OV-3 (for example, ATCC HTB-77), the ovarian cancer cell OVMANA (for example, JCRB JCRB1045), the cervical cancer HeLa (for example, ATCC CCL-2), the colon cancer cell RKO (for example, ATCC CRL-2577), the colon cancer cell HT-29 (for example, ATCC HTB-38), the colon cancer Colo 205 (for example, ATCC CCL-222), the colon cancer SW620 (for example, ATCC CCL-227), the colorectal carcinoma HCT 116 (for example, ATCC CCL-247), the pancreatic cancer cell BxPC-3 (for example, ATCC CRL-1687), the bone osteosarcoma U-2 OS (for example, ATCC HTB-96), the prostate cancer cell LNCaP clone FGC (for example, ATCC CRL-1740), the hepatocellular carcinoma JHH-4 (for example, JCRB JCRB0435), the mesothelioma NCI-H28 (for example, ATCC CRL-5820), the cervical cancer cell SiHa (for example, ATCC HTB-35), and the gastric cancer cell Kato III (for example, RIKEN BRC RCB2088). ..



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    MYPT1 suppressed ccRCC metastasis in vivo . (A) The lung metastasis model showed that MYPT1 overexpression significantly inhibited ccRCC lung metastasis. Representative gross images of the lungs and bioluminescence images of lung metastases are shown. Arrows indicate pulmonary metastatic nodules. Scale bars: 500 μm. (B, C) Nude mice injected with MYPT1‐overexpressing <t>Caki1</t> cells had fewer and smaller lung metastases. Representative images of HE staining of the lungs and statistical analysis results are shown. Scale bars: 200 or 50 μm. The pulmonary metastatic nodules were counted under a microscope, and the results were summarized. Data presented as mean ± SEM ( n = 5). Statistical analysis was performed with a two‐tailed unpaired Student's t test (* P < 0.05). ccRCC, renal clear cell carcinoma; HE, haematoxylin–eosin; MYPT1, myosin phosphatase target subunit 1.
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    MYPT1 suppressed ccRCC metastasis in vivo . (A) The lung metastasis model showed that MYPT1 overexpression significantly inhibited ccRCC lung metastasis. Representative gross images of the lungs and bioluminescence images of lung metastases are shown. Arrows indicate pulmonary metastatic nodules. Scale bars: 500 μm. (B, C) Nude mice injected with MYPT1‐overexpressing <t>Caki1</t> cells had fewer and smaller lung metastases. Representative images of HE staining of the lungs and statistical analysis results are shown. Scale bars: 200 or 50 μm. The pulmonary metastatic nodules were counted under a microscope, and the results were summarized. Data presented as mean ± SEM ( n = 5). Statistical analysis was performed with a two‐tailed unpaired Student's t test (* P < 0.05). ccRCC, renal clear cell carcinoma; HE, haematoxylin–eosin; MYPT1, myosin phosphatase target subunit 1.
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    Image Search Results


    MYPT1 suppressed ccRCC metastasis in vivo . (A) The lung metastasis model showed that MYPT1 overexpression significantly inhibited ccRCC lung metastasis. Representative gross images of the lungs and bioluminescence images of lung metastases are shown. Arrows indicate pulmonary metastatic nodules. Scale bars: 500 μm. (B, C) Nude mice injected with MYPT1‐overexpressing Caki1 cells had fewer and smaller lung metastases. Representative images of HE staining of the lungs and statistical analysis results are shown. Scale bars: 200 or 50 μm. The pulmonary metastatic nodules were counted under a microscope, and the results were summarized. Data presented as mean ± SEM ( n = 5). Statistical analysis was performed with a two‐tailed unpaired Student's t test (* P < 0.05). ccRCC, renal clear cell carcinoma; HE, haematoxylin–eosin; MYPT1, myosin phosphatase target subunit 1.

    Journal: FEBS Open Bio

    Article Title: MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8 /N‐cadherin pathway

    doi: 10.1002/2211-5463.13487

    Figure Lengend Snippet: MYPT1 suppressed ccRCC metastasis in vivo . (A) The lung metastasis model showed that MYPT1 overexpression significantly inhibited ccRCC lung metastasis. Representative gross images of the lungs and bioluminescence images of lung metastases are shown. Arrows indicate pulmonary metastatic nodules. Scale bars: 500 μm. (B, C) Nude mice injected with MYPT1‐overexpressing Caki1 cells had fewer and smaller lung metastases. Representative images of HE staining of the lungs and statistical analysis results are shown. Scale bars: 200 or 50 μm. The pulmonary metastatic nodules were counted under a microscope, and the results were summarized. Data presented as mean ± SEM ( n = 5). Statistical analysis was performed with a two‐tailed unpaired Student's t test (* P < 0.05). ccRCC, renal clear cell carcinoma; HE, haematoxylin–eosin; MYPT1, myosin phosphatase target subunit 1.

    Article Snippet: The human kidney cancer cell lines Caki1 and 769P were commercially provided by American Type Culture Collection (ATCC) and cultured as per ATCC's guidelines.

    Techniques: In Vivo, Over Expression, Injection, Staining, Microscopy, Two Tailed Test

    RNA sequencing and bioinformatic analyses demonstrated that MYPT1 is involved in a MAPK‐related pathway in ccRCC. (A) The volcano plot shows genes differentially expressed between Caki1 cells with MYPT1 overexpression group and the negative control group ( P < 0.05). (B) KEGG analysis of the differentially expressed genes (¦log2FC¦ > 1, FDR‐adjusted P < 0.05) was performed in Caki1‐NC and Caki1‐MYPT1 cells. (C) GSEA revealed that the MAPK signalling pathway gene set was less enriched in Caki1‐MYPT1 cells (FDR < 25% and P < 0.05). (D) KEGG analysis of the MYPT1‐correlated genes ( P < 0.05) in the TCGA‐KIRC dataset. (E) The 17 overlapping genes were enriched in the MAPK pathway based on the differentially expressed genes from RNA sequencing data or MYPT1‐correlated genes from TCGA‐KIRC dataset. ccRCC, renal clear cell carcinoma; GSEA, Gene Set Enrichment Analysis; KEGG, Kyoto Encyclopedia of Genes and Genomes; MAPK, mitogen‐activated protein kinase; MYPT1, myosin phosphatase target subunit 1.

    Journal: FEBS Open Bio

    Article Title: MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8 /N‐cadherin pathway

    doi: 10.1002/2211-5463.13487

    Figure Lengend Snippet: RNA sequencing and bioinformatic analyses demonstrated that MYPT1 is involved in a MAPK‐related pathway in ccRCC. (A) The volcano plot shows genes differentially expressed between Caki1 cells with MYPT1 overexpression group and the negative control group ( P < 0.05). (B) KEGG analysis of the differentially expressed genes (¦log2FC¦ > 1, FDR‐adjusted P < 0.05) was performed in Caki1‐NC and Caki1‐MYPT1 cells. (C) GSEA revealed that the MAPK signalling pathway gene set was less enriched in Caki1‐MYPT1 cells (FDR < 25% and P < 0.05). (D) KEGG analysis of the MYPT1‐correlated genes ( P < 0.05) in the TCGA‐KIRC dataset. (E) The 17 overlapping genes were enriched in the MAPK pathway based on the differentially expressed genes from RNA sequencing data or MYPT1‐correlated genes from TCGA‐KIRC dataset. ccRCC, renal clear cell carcinoma; GSEA, Gene Set Enrichment Analysis; KEGG, Kyoto Encyclopedia of Genes and Genomes; MAPK, mitogen‐activated protein kinase; MYPT1, myosin phosphatase target subunit 1.

    Article Snippet: The human kidney cancer cell lines Caki1 and 769P were commercially provided by American Type Culture Collection (ATCC) and cultured as per ATCC's guidelines.

    Techniques: RNA Sequencing, Over Expression, Negative Control